TAUROPACETM CARDIAC DEVICE IRRIGATION
▪ Locally delivered, adjunctive antimicrobial protection
prevents CIED infections
▪ Polyvinylpyrrolidone locally elutes taurolidine to reach MIC
tissue concentrations within 2 hours of use
▪ Does not contain antibiotics
No resistance patterns observed
▪ Liquid solution – no foreign body nidus for potential
infection
▪ After delivering all antimicrobial actions, Taurine is the
only leftover – Taurine enhances wound healing
CURRENT PROPHYLAXIS FOR CARDIAC DEVICE INFECTION
TAUROPACETM IRRIGATION
PRE-OPERATIVELY1,2
▪ preoperative antibiotic
administration in 90% of
all Cardiac Implantable
Electronic Device
(CIED) implants with
cephalosporins or
vancomycin
ROUTINELY
PERI-OPERATIVELY1,2
▪ approximately 75-90%
conduct perioperative
antibiotic or antimicrobial
pocket (surgical site)
irrigation
TYPICALLY
POST-OPERATIVELY1,2
▪ prolonged antibiotic
therapy postoperatively
▪ Postoperative IV
antibiotic administration
OCCASIONALLY